Cisplatin dialyse
WebJan 17, 2014 · Cisplatin is a widely used and highly effective cytotoxic agent, including for nasopharyngeal carcinoma (NPC). One of the side effects of cisplatin is nephrotoxicity, especially in tubulus.... WebHydration is essential for all patients to prevent cisplatin-induced nephrotoxicity. Specifically, short-duration, low-volume, outpatient hydration with magnesium supplementation and mannitol forced diuresis (in select patients) represent best practice principles for the safe use of cisplatin. …
Cisplatin dialyse
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WebCisplatin is also sometimes used to treat head and neck cancer (including cancer of the mouth, lip, cheek, tongue, palate, throat, tonsils, and sinuses), lung cancer, cancer of the … WebThe alcohol extract was administered orally for ten days at two dose levels of 250 and 500 mg/kg body weight, five days after administration of a single i.p. dose of cisplatin (5 mg/kg). Renal dysfunction was evaluated histologically by light microscopy and biochemically by measuring the concentrations of blood urea nitrogen, serum creatinine ...
WebMar 23, 2024 · For nearly five decades, cisplatin has played an important role as a standard chemotherapeutic agent and been prescribed to 10-20% of all cancer patients. WebMain outcome measure: Cisplatin dose in mg/m(2) based on kidney function and according to the dosing recommendations. Results: Conclusion: Cisplatin dose …
WebJun 18, 2024 · The current use of cisplatin in regimens involving pre and posthydration with careful monitoring of diuresis in the treatment of testicular tumors is associated with … WebAug 6, 2014 · Cisplatin (dichlorodiamino platinum) is an inorganic platinum-based chemotherapeutic agent that is widely used in the treatment of a variety of solid malignant tumors such as head and neck, lung, testis, ovarian, and bladder cancers [9].
WebThe mean renal clearance of cisplatin exceeds creatinine clearance and is 62 and 50 mL/min/m2 following administration of 100 mg/m2 as 2-hour or 6- to 7-hour infusions, …
WebCisplatin induced-renal dysfunction may alter the clearance of melphalan. Melphalan clearance is decreased in patients with renal impairment. Methotrexate: (Moderate) Closely monitor renal function and watch for methotrexate-related adverse reactions if concomitant use of cisplatin and methotrexate is necessary. Cisplatin and methotrexate are ... grant park atlanta homesWebPRODUCT INFORMATION – DBL™ CISPLATIN INJECTION(CISPLATIN) 1. NAME OF THE MEDICINE Cisplatin 2. QUALITATIVE AND QUANTITATIVE COMPOSITION … grant park baltic sdWebNational Center for Biotechnology Information grant park at prestwickWebSep 18, 2024 · NCBI Bookshelf chip icloud appWebCisplatin Injection is a clear, colorless, sterile aqueous solution. Each 100 mL amber vial of Cisplatin Injection contains: 1 mg per mL cisplatin USP, 9 mg per mL sodium chloride, hydrochloric acid and/or sodium hydroxide … grant park beach milwaukeeWebSep 15, 2024 · Cisplatin (cisplatin injection) (cis-diamminedichloroplatinum) is a heavy metal complex containing a central atom of platinum surrounded by two chloride atoms … grant park candlelight tourWebFeb 16, 2016 · Purpose: Loco-regional control and organ preservation are significantly improved with concomitant cisplatin/radiotherapy and are compromised with less than 5% grade 3 nephrotoxicity (creatinine clearance 15–29 mL/min). However, although clinically important, in none of the randomized trials is grade 2 nephrotoxicity (defined as … chip icing