WebMay 9, 2007 · The human MxA gene belongs to the class of interferon (IFN)-stimulated genes (ISGs) involved in antiviral resistance against influenza viruses. Here, we studied the requirements for MxA induction by influenza A virus infection. MxA is transcriptionally upregulated by type I (alpha and beta) and type III (lambda) IFNs. WebSep 24, 2007 · The objective of this study was to find potential biomarkers for predicting sustained virologic responses to interferon-α (IFN-α) treatment in chronic hepatitis B (CHB) patients. A total of 101 CHB patients were treated with pegylated IFN-α2a for 48 weeks and followed up for 24 weeks, including 34 IFN responders (IFN-Rs) and 67 IFN nonresponders …
The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection
WebMay 1, 2024 · During the induction phase, methanol was fed by pulsed addition at a rate of 20 g h −1, in order to facilitate an optimal substrate concentration of 1·4% v/v throughout the experiment. A known quantity of methanol was added as pulse, followed by collection of significant samples, until it was consumed at different time points in the ... WebOct 16, 2013 · The interferon-inducible myxovirus resistance (Mx) proteins play important roles in combating a wide range of virus infections. MxA inhibits many RNA and DNA … freerunning wikipedia
Induction of MxA gene expression by influenza A virus requires …
WebFeb 12, 2016 · The aim of this study is to investigate whether induction of myxovirus resistance protein A (MxA) mRNA after 3 months of interferon-β administration is related … WebFeb 1, 1991 · Mx induction was found in the spleens of mice treated with TNF-alpha or IL-1 alpha, but this effect could be neutralized with antibodies to murine IFN-alpha/beta. Of the other cytokines that we tested (IL-2, IL-6, and granulocyte-macrophage colony-stimulating factor), only IL-2 induced the Mx genes in peripheral blood mononuclear cells, but ... WebOct 16, 2013 · Their expression is inducible by type I and type III interferons. Mx proteins are high-molecular-weight guanosine triphosphatases (GTPases) and belong to the dynamin super family ( Praefcke and McMahon, 2004 ). Humans have two Mx genes, called MxA and MxB, which reside on the long arm of chromosome 21 ( Aebi et al., 1989 ). free run online game